Adeno-associated virus (AAV) is one of the most promising viral vectors for gene therapy and cell therapy. As with any potential therapeutic system, it needs to be thoroughly understood at both in vitro and in vivo levels. With years of AAV vector characterization experience and advanced equipment, we are dedicated to helping to better understand AAV vectors and promote their application for in vitro or in vivo research. Adeno Associated Virus Vector Imaging Services https://iem.creative-biostruct....ure.com/aav-vector-c

As a kind of technology that uses a high energy electron beam to detect objects at nano-scale level, SEM can generate valuable information about various specimens, including shape and size of the particles (morphological information), surface features (topographic information), the elements and compounds (information about the composition), and the arrangement of the objects (crystallographic information). Insect Imaging Services https://iem.creative-biostruct....ure.com/insect-scien

Creative Biostructure has a comprehensive computer-aided drug design (CADD) platform, which enables us to offer custom in silico virtual screening services. The optimized virtual screening procedure can reduce the number of compounds to be experimentally screened, improve the possibility of ideal lead discovery, and reduce the risk of failure of later lead optimization, thereby winning valuable time for your project on the development of novel drugs. virtual screening of chemical libraries https://drug-discovery.creativ....e-biostructure.com/i

As a leading service provider in the field of structural biology, relying on the first-class structural biology technology platform that covers X-ray crystallography, cryo-electron microscopy (Cryo-EM) technology and protein NMR spectroscopy, Creative Biostructure provides a comprehensive solution of target structure determination, called MagHelix™ Gene-to-Protein and Gene-to-Structure, complemented with the most advanced biophysical methods to characterize target and target-ligand interaction. Our services support structure-guided lead discovery and optimization, as well as biological drug discovery, such as therapeutic antibody di

Because most viruses are small  200 nm), standard optical microscopes are generally not suitable for direct observation of them. The use of electron microscopy (EM) to visualize the ultrastructure of viruses has become the gold standard for viral imaging, however, the complexity of preparing biological samples (fixed or frozen) and the need to place specimens under vacuum make it unsuitable for studying the dynamic processes during virus-cell interactions. Creative Biostructure is now capable of providing super-resolution imaging services using various super-resolution microscopes for your coronavirus-related research. Super-resol

There are currently no approved antiviral drugs for treating coronavirus infections. In the face of an acute outbreak, we hope to adopt a more efficient approach to develop antiviral drugs. There are two main methods for drug screening, including high-throughput screening (HTS) and virtual screening. The HTS method realizes automatic operation and sensitive detection, but the positive rate is low (less than 1/1000, thus the cost is relatively high. However, the positive rate of high-throughput virtual screening is generally around 5%-20%. And the results of virtual screening can be combined with experimental screening to complemen

Creative Biostructure is specialized in providing cost-effective contract services to both academia and biotech/pharmaceutical industries in the field of structural biology and membrane protein technologies. We have developed all-in-one, gene-to-structure pipelines for the structure determination of macromolecules of your interest. With a team of experienced professionals, Creative Biostructure is able to solve the structure of many challenging proteins including GPCRs, ion channels, transporters, enzymes and viral targets. We also provide a comprehensive list of products and other related services to facilitate your research in str

Creative Biostructure is specialized in providing cost-effective contract services to both academia and biotech/pharmaceutical industries in the field of structural biology and membrane protein technologies. We have developed all-in-one, gene-to-structure pipelines for the structure determination of macromolecules of your interest. With a team of experienced professionals, Creative Biostructure is able to solve the structure of many challenging proteins including GPCRs, ion channels, transporters, enzymes and viral targets. We also provide a comprehensive list of products and other related services to facilitate your research in str

Kinases and phosphatases play a crucial role in biological functions. They control nearly every cellular process and are involved in a wide variety of pathological conditions. With years of accumulated experience, Creative Biomart has built a powerful scientific team and a fully integrated platform for kinase/phosphatase biology to provide one-stop services and customizable solutions to fully meet specific requirements of our customers. Synthesis of Phospho-Amino Acid Analogues https://www.kinasebiotech.com/....synthesis-of-phospho

Kinases and phosphatases play a crucial role in biological functions. They control nearly every cellular process and are involved in a wide variety of pathological conditions. With years of accumulated experience, Creative Biomart has built a powerful scientific team and a fully integrated platform for kinase/phosphatase biology to provide one-stop services and customizable solutions to fully meet specific requirements of our customers. Kinase/Phosphatase Assay Development and Validation https://www.kinasebiotech.com/....kinase-phosphatase-a