RDC is composed of four parts, including radionuclide, chelator, linker, and targeting biomolecule. After the connection between radioactive particle and chelator, this complex needed to binding to the targeting molecule by a linker to avoid interferences between bioactive groups in RDC. The linker in the RDC, also named as PKM (Pharmacokinetic Modifying) linker, has a significant effect on radiotracer excretion kinetics of RDC to improve the T/B (target-to-background) ratios of the radiopharmaceutical. https://www.rdcthera.com/linke....r-design-and-synthes

Collagen is the most abundant and widely distributed functional protein in mammals, accounting for 25 % to 30 % of total protein. Collagen is a natural protein of the muscle, which has greater affinity for protein molecules on the skin surface, weaker antigenicity, good biocompatibility and biodegradation safety. Therefore collagen has gained wide application in food, medicine, tissue engineering, cosmetics and other fields. https://www.3dmicroflu.com/pro....tein-based-bioinks.h

Most biological studies involve cell research. Living cell imaging, whether observed with the naked eye by camera or microscope, has become one of the most important parts in biological research. One of the tools for imaging living cells with high sensitivity and specificity is fluorescence microscope. Due to the small number of endogenous fluorescent molecules, probes and antibodies labeled with fluorescent labels can reveal the location of specific molecules in cells. https://www.bioimagingtech.com..../label-free-live-cel

Signaling pathways link extracellular cues to cellular responses, so that cells are able to adapt to the changes in the environment. The signals are processed as a series of molecular events in cells. Proteins responsible for detecting the signal are termed receptors or sensors, which are the first nodes in signaling transduction pathways. https://www.cd-biosciences.com..../receptors-sensors.h

Apoptosis & Cell Death | #cell Death